We present here a novel platform combination, using a multifunctional pipette to individually electroporate single-cells and to locally deliver an analyte, while in their culture environment. We demonstrate a method to fabricate low-resistance metallic electrodes into a PDMS pipette, followed by characterization of its effectiveness, benefits and limits in comparison with an external carbon microelectrode.
A. Ainla, S. Xu, N. Sanchez, G. D. M. Jeffries and A. Jesorka, Lab Chip, 2012, 12, 4605 DOI: 10.1039/C2LC40563F
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