Issue 20, 2012
From the journal:

Organic & Biomolecular Chemistry

Coumarin-based chiral fluorescence sensor incorporating a thiourea unit for highly enantioselective recognition of N-Boc-protected proline†

Zhitao Xing,a   Yong Fu,a   Jiecong Zhou,a   Chengjian Zhu*ab  and  Yixiang Cheng*a  

* Corresponding authors

a State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, PR China
E-mail: cjzhu@nju.edu.cn
Fax: +86 25 83584886

b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Abstract

New coumarin-based chiral thiourea sensor 1 was found to be an enantioselective fluorescent chemosensor for N-Boc-protected proline. The chiral sensor shows lower background fluorescence, and higher fluorescence enhancement with 18 nm blue shifts. Job plot analysis result indicates that sensor 1 can form a 1 : 1 stoichiometric complex and it could be used as a fluorescence sensor for the determination of enantiomer composition of N-Boc-protected proline.

Graphical abstract: Coumarin-based chiral fluorescence sensor incorporating a thiourea unit for highly enantioselective recognition of N-Boc-protected proline

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2OB25311A
Article type
Paper
Submitted
12 Feb 2012
Accepted
21 Mar 2012
First published
13 Apr 2012

Org. Biomol. Chem., 2012,10, 4024-4028

Permissions

Request permissions

Coumarin-based chiral fluorescence sensor incorporating a thiourea unit for highly enantioselective recognition of N-Boc-protected proline

Z. Xing, Y. Fu, J. Zhou, C. Zhu and Y. Cheng, Org. Biomol. Chem., 2012, 10, 4024 DOI: 10.1039/C2OB25311A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements