Issue 1, 2012
From the journal:

RSC Advances

ortho-Nitrobenzyl alcohol based two-photon excitation controlled drug release system

Xing Wang,a   Stefan Werner,b   Thomas Weiß,b   Klaus Liefeithb  and  Christian Hoffmann*b  

* Corresponding authors

a Department of Chemistry, University of Victoria, Victoria, British Columbia. V8P5C2, Canada

b Institute for Bioprocessing and Analytical Measurement Techniques, Rosenhof, HeilbadHeiligenstadt, Germany
E-mail: christian.hoffmann@iba-heiligenstadt.de
Fax: +49 3606 671200
Tel: +49 3606 671600

Abstract

Controlled drug delivery is highly desired for many medicinal cases where time and spatial dependency is required. The present paper provides a promising but also simple molecular architecture for photoinduced release of chemical compounds with primary amines based on one-and two-photon absorption. Silane coupling to the surface and biotin/streptavidin chemistry ensure the stability of the system.

Graphical abstract: ortho-Nitrobenzyl alcohol based two-photon excitation controlled drug release system

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Article information

DOI
https://doi.org/10.1039/C1RA00599E
Article type
Paper
Submitted
16 Aug 2011
Accepted
26 Sep 2011
First published
01 Nov 2011

RSC Adv., 2012,2, 156-160

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ortho-Nitrobenzyl alcohol based two-photon excitation controlled drug release system

X. Wang, S. Werner, T. Weiß, K. Liefeith and C. Hoffmann, RSC Adv., 2012, 2, 156 DOI: 10.1039/C1RA00599E

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