Issue 7, 2012
From the journal:

RSC Advances

Shear flow-induced nanotubulation of surface-immobilized liposomes

Yurina Sekine,ab   Keita Abe,a   Akitaka Shimizu,a   Yoshihiro Sasaki,†*ac   Shin-ichi Sawadad  and  Kazunari Akiyoshi†*abd  

* Corresponding authors

a Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Kanda-Surugadai, Chiyoda-ku, Tokyo, Japan
E-mail: ysasaki.org@tmd.ac.jp

b Global Center of Excellence (GCOE) Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Tokyo Medical and Dental University, Japan

c PRESTO, Japan Science and Technology Agency, Japan

d Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Japan
E-mail: akiyoshi@bio.polym.kyoto-u.ac.jp

Abstract

We propose a simple method to prepare lipid nanotubes, which can be used to transport biological molecules. By applying shear stress to surface-immobilized liposomes on a solid substrate, we obtained long lipid nanotubes arranged in a well-controlled direction.

Graphical abstract: Shear flow-induced nanotubulation of surface-immobilized liposomes

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Article information

DOI
https://doi.org/10.1039/C2RA00629D
Article type
Communication
Submitted
23 Aug 2011
Accepted
11 Jan 2012
First published
16 Feb 2012

RSC Adv., 2012,2, 2682-2684

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Shear flow-induced nanotubulation of surface-immobilized liposomes

Y. Sekine, K. Abe, A. Shimizu, Y. Sasaki, S. Sawada and K. Akiyoshi, RSC Adv., 2012, 2, 2682 DOI: 10.1039/C2RA00629D

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