Issue 8, 2012
From the journal:

RSC Advances

Efficient, rapid synthesis of bis(indolyl)methane using ethyl ammonium nitrate as an ionic liquid

Shafeek A. R. Mulla,*a   A. Sudalai,a   Mohsinkhan Y. Pathan,a   Shafi A. Siddique,a   Suleman M. Inamdar,a   Santosh S. Chavana  and  R. Santosh Reddya  

* Corresponding authors

a Chemical Engineering & Process Development Division, National Chemical Laboratory, Dr Homi Bhabha Road, Pune-411008, Maharashtra, India
E-mail: sa.mulla@ncl.res.in
Fax: +91-20-25902676
Tel: +91-20-25902316

Abstract

A simple and rapid protocol has been developed for an efficient synthesis of bis(indolyl)methane in excellent yields using ethyl ammonium nitrate (EAN) as reusable ionic liquid at room temperature. The protocol involves an electrophilic substitution reaction of indoles with several aldehydes.

Graphical abstract: Efficient, rapid synthesis of bis(indolyl)methane using ethyl ammonium nitrate as an ionic liquid

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Article information

DOI
https://doi.org/10.1039/C2RA00849A
Article type
Paper
Submitted
05 Oct 2011
Accepted
27 Jan 2012
First published
02 Mar 2012

RSC Adv., 2012,2, 3525-3529

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Efficient, rapid synthesis of bis(indolyl)methane using ethyl ammonium nitrate as an ionic liquid

S. A. R. Mulla, A. Sudalai, M. Y. Pathan, S. A. Siddique, S. M. Inamdar, S. S. Chavan and R. S. Reddy, RSC Adv., 2012, 2, 3525 DOI: 10.1039/C2RA00849A

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