Issue 7, 2012
From the journal:

RSC Advances

Lipase-catalyzed regioselective acylation of sugar in microreactors†

Li-Hua Du*a  and  Xi-Ping Luob  

* Corresponding authors

a College of Pharmaceutical Science, ZheJiang University of Technology, Hangzhou, China
E-mail: orgdlh@yahoo.com.cn, orgdlh@zjut.edu.cn
Fax: +86 571 88320903

b Department of Environmental Science and Technology, ZheJiang A&F University, Hangzhou, China

Abstract

The highly regioselective synthesis of sugar 6-monoesters with sugar and vinyl carboxylate in a flow microreactor using Lipozyme TL IM from Thermomyces lanuginosus as a catalyst has been developed. The important features of this method include mild reaction conditions, short reaction times (30 min), high yields and high regioselectivities.

Graphical abstract: Lipase-catalyzed regioselective acylation of sugar in microreactors

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Article information

DOI
https://doi.org/10.1039/C2RA01112C
Article type
Communication
Submitted
16 Nov 2011
Accepted
09 Jan 2012
First published
10 Feb 2012

RSC Adv., 2012,2, 2663-2665

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Lipase-catalyzed regioselective acylation of sugar in microreactors

L. Du and X. Luo, RSC Adv., 2012, 2, 2663 DOI: 10.1039/C2RA01112C

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