Issue 13, 2012
From the journal:

RSC Advances

Formation of unexpected α-amino amidine through three-component ‘UGI condensation reaction’†

Abu T. Khan,*a   Sidick Basha R,a   Mohan Lala  and  Mohammad Hedayetullah Mirb  

* Corresponding authors

a Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, India
E-mail: atk@iitg.ernet.in
Fax: +91 361 2582349
Tel: +91 361 2582305

b Department of Chemistry, Aliah University, DN41 Salt Lake, Kolkata 700 091, India

Abstract

The synthesis of a wide variety of α-amino amidine derivatives was accomplished through a one-pot three-component reaction from aromatic aldehydes, aromatic amines and isocyanides, catalyzed by bromodimethylsulfonium bromide (BDMS), in good yields. Some of the salient features of the present protocol are: mild reaction conditions, shorter reaction times, non-aqueous work-up procedure and no need for chromatographic separation.

Graphical abstract: Formation of unexpected α-amino amidine through three-component ‘UGI condensation reaction’

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2RA20539D
Article type
Communication
Submitted
23 Mar 2012
Accepted
20 Apr 2012
First published
20 Apr 2012

RSC Adv., 2012,2, 5506-5509

Permissions

Request permissions

Formation of unexpected α-amino amidine through three-component ‘UGI condensation reaction’

A. T. Khan, S. B. R, M. Lal and M. H. Mir, RSC Adv., 2012, 2, 5506 DOI: 10.1039/C2RA20539D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements