Issue 1, 2013

An ascorbic acid sensor based on protein-modified Au nanoclusters

Abstract

A simple fluorescence sensor for sensitive turn-off detection of ascorbic acid (AA) was developed by using protein-modified Au nanoclusters in aqueous media. The sensing mechanism is originated from the oxidation state change of Au nanoclusters controlled by AA. Under optimal experimental conditions, a good linear relationship between the relative fluorescence quenching intensity and the concentration of AA can be obtained in the range of 1.5 to 10 μM, with a detection limit as low as 0.2 μM. The proposed method is simple, efficient and reliable for monitoring of AA in some biological samples.

Graphical abstract: An ascorbic acid sensor based on protein-modified Au nanoclusters

Article information

Article type
Paper
Submitted
13 Aug 2012
Accepted
16 Oct 2012
First published
19 Oct 2012

Analyst, 2013,138, 229-233

An ascorbic acid sensor based on protein-modified Au nanoclusters

X. Wang, P. Wu, X. Hou and Y. Lv, Analyst, 2013, 138, 229 DOI: 10.1039/C2AN36112D

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