Issue 10, 2013
From the journal:

Biomaterials Science

Solid-supported DNA for asymmetric synthesis: a stepping-stone toward practical applications†

Soyoung Park,*a   Keiichi Ikehataa  and  Hiroshi Sugiyama*abc  

* Corresponding authors

a Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan

b Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Yoshida-ushinomiyacho, Sakyo-ku, Kyoto 606-8501, Japan

c CREST, Japan Science and Technology Corporation (JST), Sanbancho, Chiyoda-ku, Tokyo 102-0075, Japan
E-mail: hs@kuchem.kyoto-u.ac.jp
Fax: (+)81-75-753-3670
Tel: (+)81-75-753-4002

Abstract

We developed an affordable solid-supported DNA and demonstrated that it could be used as a reusable chiral source for the copper(II)-catalyzed Diels–Alder reaction in water. This study will be a valuable stepping-stone for the industrial application of DNA-based asymmetric synthesis.

Graphical abstract: Solid-supported DNA for asymmetric synthesis: a stepping-stone toward practical applications

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Article information

DOI
https://doi.org/10.1039/C3BM60134J
Article type
Communication
Submitted
24 May 2013
Accepted
19 Jun 2013
First published
10 Jul 2013

Biomater. Sci., 2013,1, 1034-1036

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Solid-supported DNA for asymmetric synthesis: a stepping-stone toward practical applications

S. Park, K. Ikehata and H. Sugiyama, Biomater. Sci., 2013, 1, 1034 DOI: 10.1039/C3BM60134J

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