Issue 18, 2013
From the journal:

Chemical Communications

Solvent dependent reductive defluorination of aliphatic C–F bonds employing Sm(HMDS)2†

Mario Janjetovic,a   Annika M. Träff,a   Tobias Ankner,a   Jenny Wettergrena  and  Göran Hilmersson*a  

* Corresponding authors

a Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, Gothenburg, Sweden
E-mail: hilmers@chem.gu.se
Tel: +46-317869022

Abstract

Sm(HMDS)2 in n-hexane mediates fast cleavage of primary, secondary and tertiary alkyl fluorides in good to excellent yields. In n-hexane Sm(HMDS)2 exhibits uniquely enhanced reductive ability towards the C–F bond compared to when using THF as solvent.

Graphical abstract: Solvent dependent reductive defluorination of aliphatic C–F bonds employing Sm(HMDS)2

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Article information

DOI
https://doi.org/10.1039/C3CC37828D
Article type
Communication
Submitted
29 Oct 2012
Accepted
09 Jan 2013
First published
10 Jan 2013

Chem. Commun., 2013,49, 1826-1828

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Solvent dependent reductive defluorination of aliphatic C–F bonds employing Sm(HMDS)2

M. Janjetovic, A. M. Träff, T. Ankner, J. Wettergren and G. Hilmersson, Chem. Commun., 2013, 49, 1826 DOI: 10.1039/C3CC37828D

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