Issue 28, 2013
From the journal:

Chemical Communications

Acoustically controlled enhancement of molecular sensing to assess oxidative stress in cells†‡

Julien Reboud,a   Craig Auchinvole,a   Christopher D. Syme,a   Rab Wilsona  and  Jonathan M. Cooper*a  

* Corresponding authors

a Division of Biomedical Engineering, University of Glasgow, Oakfield Avenue, Glasgow, UK
E-mail: jon.cooper@glagsow.ac.uk
Fax: +44 (0)141-330 4907
Tel: +44 (0)141-330 5231

Abstract

We demonstrate a microfluidic platform for the controlled aggregation of colloidal silver nanoparticles using surface acoustic waves (SAWs), enabling surface enhanced Raman scattering (SERS) analysis of oxidative damage in cells. We show that by varying the frequency and the power of the acoustic energy, it is possible to modulate the aggregation of the colloid within the sample and hence to optimise the SERS analysis.

Graphical abstract: Acoustically controlled enhancement of molecular sensing to assess oxidative stress in cells

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Article information

DOI
https://doi.org/10.1039/C3CC37931K
Article type
Communication
Submitted
01 Nov 2012
Accepted
15 Feb 2013
First published
18 Feb 2013
This article is Open Access

Chem. Commun., 2013,49, 2918-2920

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Acoustically controlled enhancement of molecular sensing to assess oxidative stress in cells

J. Reboud, C. Auchinvole, C. D. Syme, R. Wilson and J. M. Cooper, Chem. Commun., 2013, 49, 2918 DOI: 10.1039/C3CC37931K

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