Dual 1,3-dipolar cycloaddition of carbon dioxide: two CO bonds of CO2 react in one reaction

Abstract

The first investigation into two CO bonds of CO₂ reacting in one reaction through dual 1,3-dipolar cycloaddition of CO₂ with isocyanides and dialkyl acetylenedicarboxylates has been reported. The reaction proceeded efficiently at 80 °C at a pressure of 1 atm of CO₂, affording symmetric 1,6-dioxospiro[4,4]nonane-3,8-diene derivatives in moderate yields.