Issue 28, 2013
From the journal:

Chemical Communications

RNA-templated DNA origami structures†‡

Masayuki Endo,*ab   Seigi Yamamoto,c   Koichi Tatsumi,c   Tomoko Emura,c   Kumi Hidakac  and  Hiroshi Sugiyama*abc  

* Corresponding authors

a Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Yoshida-ushinomiyacho, Sakyo-ku, Kyoto 606-8501, Japan
E-mail: endo@kuchem.kyoto-u.ac.jp, hs@kuchem.kyoto-u.ac.jp
Fax: +81-75-753-3670

b CREST, Japan Science and Technology Corporation (JST), Sanbancho, Chiyoda-ku, Tokyo 102-0075, Japan

c Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan

Abstract

Using the RNA transcript as a template, RNA-templated DNA origami structures were constructed by annealing with designed DNA staple strands. RNA-templated DNA origami structures were folded to form seven-helix bundled rectangular structures and six-helix bundled tubular structures. The chemically modified RNA–DNA hybrid origami structures were prepared by using RNA templates containing modified uracils.

Graphical abstract: RNA-templated DNA origami structures

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Article information

DOI
https://doi.org/10.1039/C3CC38804B
Article type
Communication
Submitted
07 Dec 2012
Accepted
18 Feb 2013
First published
19 Feb 2013

Chem. Commun., 2013,49, 2879-2881

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RNA-templated DNA origami structures

M. Endo, S. Yamamoto, K. Tatsumi, T. Emura, K. Hidaka and H. Sugiyama, Chem. Commun., 2013, 49, 2879 DOI: 10.1039/C3CC38804B

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