Issue 42, 2013
From the journal:

Chemical Communications

Visualization of UV-induced damage on single DNA molecules†

Jinyong Lee,a   Hyun Seung Park,a   Sangyong Limb  and  Kyubong Jo*a  

* Corresponding authors

a Department of Chemistry and Interdisciplinary Program of Integrated Biotechnology, Sogang University, Seoul 121-742, Korea
E-mail: jokyubong@sogang.ac.kr
Fax: +82 2 715-7893
Tel: +82 2 705 8881

b Research Division for Biotechnology, Korea Atomic Energy Research Institute, Jeongeup 580-185, Korea
E-mail: saylim@kaeri.re.kr
Tel: +82 63 570-3141

Abstract

Ultraviolet radiation induced DNA damage such as double stranded breaks and single stranded breaks is visualized at the level of single DNA molecules. Molecular observations provide a map of DNA radiation-mediated breakages, revealing the sequence dependency of DNA damage rather than random occurrences.

Graphical abstract: Visualization of UV-induced damage on single DNA molecules

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Article information

DOI
https://doi.org/10.1039/C3CC38884K
Article type
Communication
Submitted
12 Dec 2012
Accepted
23 Jan 2013
First published
23 Jan 2013

Chem. Commun., 2013,49, 4740-4742

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Visualization of UV-induced damage on single DNA molecules

J. Lee, H. S. Park, S. Lim and K. Jo, Chem. Commun., 2013, 49, 4740 DOI: 10.1039/C3CC38884K

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