Issue 18, 2013
From the journal:

Chemical Communications

pH dependent multifunctional and multiply-configurable logic gate systems based on small molecule G-quadruplex DNA recognition†

Sudipta Bhowmik,ab   Rabindra Nath Das,b   Bibudha Parasarb  and  Jyotirmayee Dash*ab  

* Corresponding authors

a Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata-700032, India
E-mail: ocjd@iacs.res.in
Fax: +91-33-2473-2805
Tel: +91-33-2473-4971, ext 1405

b Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, West Bengal 741252, India

Abstract

A variety of logic operations such as XNOR, NOR, AND, NAND, NOT have been designed with pH as an external modulator by choosing thiazole orange (TO) and a c-kit2 promoter quadruplex as two inputs and fluorescence signals of pyridyl bis-indole amide (PBIA) and TO as two outputs.

Graphical abstract: pH dependent multifunctional and multiply-configurable logic gate systems based on small molecule G-quadruplex DNA recognition

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Article information

DOI
https://doi.org/10.1039/C3CC38888C
Article type
Communication
Submitted
12 Dec 2012
Accepted
14 Jan 2013
First published
14 Jan 2013

Chem. Commun., 2013,49, 1817-1819

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pH dependent multifunctional and multiply-configurable logic gate systems based on small molecule G-quadruplex DNA recognition

S. Bhowmik, R. N. Das, B. Parasar and J. Dash, Chem. Commun., 2013, 49, 1817 DOI: 10.1039/C3CC38888C

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