The synthesis and characterization of a highly photostable bromo-substituted BODIPY dye (I) fused-ring-expanded with thienopyrrole moieties is reported. The results of MTT assays and flow cytometric analyses in living HeLa cells demonstrate that I has a high singlet oxygen quantum yield (ΦΔ = 0.63) and exhibits photocytotoxicity upon irradiation in the NIR region making it potentially suitable for use in PDT.
Y. Yang, Q. Guo, H. Chen, Z. Zhou, Z. Guo and Z. Shen, Chem. Commun., 2013, 49, 3940 DOI: 10.1039/C3CC40746B
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