Issue 36, 2013
From the journal:

Chemical Communications

Polysaccharide-lecithin reverse micelles with enzyme-degradable triglyceride shell for overcoming tumor multidrug resistance†

Chia-Wei Su,a   San-Yuan Chen*a  and  Dean-Mo Liu*a  

* Corresponding authors

a Department of Materials Sciences and Engineering, National Chiao Tung University, Hsinchu, Taiwan
E-mail: sanyuanchen@mail.nctu.edu.tw, deanmo_liu@yahoo.ca
Fax: +886-3-5724727
Tel: +886-3-5712121

Abstract

A newly-designed drug carrier with enzyme-triggered release behavior and the ability to circumvent multidrug resistance was successfully developed. By optimizing the ratio of lecithin and polysaccharide in reverse micelles, encapsulation efficiency and encapsulation stability can be significantly improved.

Graphical abstract: Polysaccharide-lecithin reverse micelles with enzyme-degradable triglyceride shell for overcoming tumor multidrug resistance

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Article information

DOI
https://doi.org/10.1039/C3CC40836A
Article type
Communication
Submitted
31 Jan 2013
Accepted
21 Mar 2013
First published
21 Mar 2013

Chem. Commun., 2013,49, 3772-3774

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Polysaccharide-lecithin reverse micelles with enzyme-degradable triglyceride shell for overcoming tumor multidrug resistance

C. Su, S. Chen and D. Liu, Chem. Commun., 2013, 49, 3772 DOI: 10.1039/C3CC40836A

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