Issue 47, 2013
From the journal:

Chemical Communications

Red blood cells decorated with functionalized core–shell magnetic nanoparticles: elucidation of the adsorption mechanism†

Thanh Duc Mai,abc   Fanny d'Orlyé,b   Christine Ménager,a   Anne Varenne*b  and  Jean-Michel Siaugue*a  

* Corresponding authors

a UPMC University of Paris 06-CNRS-ESPCI Laboratoire Physicochimie des Electrolytes, Colloïdes et Sciences Analytiques PECSA UMR 7195, 4 place Jussieu, 75252 Paris, France
E-mail: christine.menager@courriel.upmc.fr

b Chimie ParisTech, Ecole Nationale Supérieure de Chimie de Paris, Imagery, Chemical and Genetic Pharmacology Unit (UPCGI), UMR CNRS 8151 – U INSERM 1022, 11, rue Pierre et Marie Curie, 75231 Paris Cedex 05, France
E-mail: anne-varenne@chimie-paristech.fr

c Centre for Environmental Technology and Sustainable Development (CETASD), Hanoi University of Science, Nguyen Trai Street 334, Hanoi, Viet Nam
E-mail: maithanhduc83@gmail.com

Abstract

The decoration of red blood cells (RBCs) with aminated and carboxylated core–shell magnetic nanoparticles (CSMNs) was studied and elucidated. It was demonstrated that only aminated CSMNs could decorate the RBCs and their adsorption interaction is mainly ruled by electrostatic attraction between the positively charged amino groups on CSMNs and the abundant sialic acid groups on the outer surface of RBCs.

Graphical abstract: Red blood cells decorated with functionalized core–shell magnetic nanoparticles: elucidation of the adsorption mechanism

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Article information

DOI
https://doi.org/10.1039/C3CC41513A
Article type
Communication
Submitted
27 Feb 2013
Accepted
18 Apr 2013
First published
18 Apr 2013

Chem. Commun., 2013,49, 5393-5395

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Red blood cells decorated with functionalized core–shell magnetic nanoparticles: elucidation of the adsorption mechanism

T. D. Mai, F. d'Orlyé, C. Ménager, A. Varenne and J. Siaugue, Chem. Commun., 2013, 49, 5393 DOI: 10.1039/C3CC41513A

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