Issue 45, 2013
From the journal:

Chemical Communications

Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells†

Ala Jo,a   Jongmin Parkb  and  Seung Bum Park*ab  

* Corresponding authors

a Department of Chemistry, Seoul National University, Seoul, Korea
E-mail: sbpark@snu.ac.kr
Fax: +82 2 884 4025
Tel: +82 2 880 9090

b Department of Biophysics and Chemical Biology/Bio-MAX Institute, Seoul National University, Seoul 151-747, Korea

Abstract

Biophysical understanding of cellular glucose uptake led us to the development of an image-based high-throughput screening system by using a fluorescent glucose bioprobe, GB2. The accuracy, robustness, and practicality of our image-based HTS system were demonstrated through the pilot screening and the subsequent in vitro confirmation.

Graphical abstract: Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC41529E
Article type
Communication
Submitted
28 Feb 2013
Accepted
16 Apr 2013
First published
17 Apr 2013

Chem. Commun., 2013,49, 5138-5140

Permissions

Request permissions

Exploiting the mechanism of cellular glucose uptake to develop an image-based high-throughput screening system in living cells

A. Jo, J. Park and S. B. Park, Chem. Commun., 2013, 49, 5138 DOI: 10.1039/C3CC41529E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements