Issue 45, 2013
From the journal:

Chemical Communications

Nona-copper(ii)-containing 18-tungsto-8-arsenate(iii) exhibits antitumor activity†

Zhen Zhou,a   Dongdi Zhang,a   Lu Yang,a   Pengtao Ma,a   Yanan Si,a   Ulrich Kortz,b   Jingyang Niu*a  and  Jingping Wang*a  

* Corresponding authors

a Henan Key Laboratory of Polyoxometalate Chemistry, Institute of Molecular and Crystal Engineering, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan, China
E-mail: jyniu@henu.edu.cn, jpwang@henu.edu.cn
Fax: +86 378 3886876
Tel: +86 378 3886876

b School of Engineering and Science, Jacobs University, P.O. Box 750 561, 28725 Bremen, Germany

Abstract

The nona-CuII-containing tungstoarsenate(III) [H4{CuII9AsIII6O15(H2O)6}(α-AsIIIW9O33)2]8− (1a) has been synthesized and characterized. Polyanion 1a comprises a unique, cylindrical {CuII9AsIII6O15(H2O)6}6+ cluster, which forms a large central cavity and is capped on either end by an [α-AsIIIW9O33]9− capping group. It exhibits remarkable activity against K562 leukaemia cells, as well as induces HepG2 cell apoptosis and autophagy.

Graphical abstract: Nona-copper(ii)-containing 18-tungsto-8-arsenate(iii) exhibits antitumor activity

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC41628C
Article type
Communication
Submitted
04 Mar 2013
Accepted
18 Apr 2013
First published
18 Apr 2013

Chem. Commun., 2013,49, 5189-5191

Permissions

Request permissions

Nona-copper(II)-containing 18-tungsto-8-arsenate(III) exhibits antitumor activity

Z. Zhou, D. Zhang, L. Yang, P. Ma, Y. Si, U. Kortz, J. Niu and J. Wang, Chem. Commun., 2013, 49, 5189 DOI: 10.1039/C3CC41628C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements