Issue 61, 2013
From the journal:

Chemical Communications

ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive†

Xifei Yu,ab   Xiaoqiang Yang,ab   Sonja Horte,ab   Jayachandran N. Kizhakkedathuabc  and  Donald E. Brooks*abc  

* Corresponding authors

a Centre for Blood Research, University of British Columbia (UBC), 2350 Health Sciences Mall, Vancouver, Canada
E-mail: don.brooks@ubc.ca
Fax: +1 604 822 7742
Tel: +1 604 822 7081

b Department of Pathology and Laboratory Medicine, UBC, 2350 Health Sciences Mall, Vancouver, Canada

c Department of Chemistry, UBC, 2350 Health Sciences Mall, Vancouver, Canada

Abstract

A new monomer, 2-(methacryloyloxy)ethyl choline phosphate, and its direct polymerization into a polyvalent choline phosphate are described, providing a universal biomembrane adhesive exhibiting rapid, strong attachment to any mammalian cell membrane and fast internalization, properties of great value in applications such as tissue engineering and drug delivery.

Graphical abstract: ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive

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Article information

DOI
https://doi.org/10.1039/C3CC41895B
Article type
Communication
Submitted
13 Mar 2013
Accepted
22 Apr 2013
First published
23 Apr 2013

Chem. Commun., 2013,49, 6831-6833

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ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive

X. Yu, X. Yang, S. Horte, J. N. Kizhakkedathu and D. E. Brooks, Chem. Commun., 2013, 49, 6831 DOI: 10.1039/C3CC41895B

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