Issue 43, 2013
From the journal:

Chemical Communications

Supramolecular filaments containing a fixed 41% paclitaxel loading†

Ran Lin,a   Andrew G. Cheetham,a   Pengcheng Zhang,a   Yi-an Lina  and  Honggang Cui*a  

* Corresponding authors

a Department of Chemical and Biomolecular Engineering, and Institute for NanoBioTechnology, The Johns Hopkins University, 3400 N Charles Street, Baltimore, MD 21218, USA
E-mail: hcui6@jhu.edu

Abstract

We report here the self-assembly of a rationally designed paclitaxel drug amphiphile into well-defined supramolecular filaments that possess a fixed 41% paclitaxel loading. These filaments can exert effective cytotoxicity against a number of cell lines comparable to that of free paclitaxel.

Graphical abstract: Supramolecular filaments containing a fixed 41% paclitaxel loading

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC41896K
Article type
Communication
Submitted
13 Mar 2013
Accepted
10 Apr 2013
First published
10 Apr 2013

Chem. Commun., 2013,49, 4968-4970

Permissions

Request permissions

Supramolecular filaments containing a fixed 41% paclitaxel loading

R. Lin, A. G. Cheetham, P. Zhang, Y. Lin and H. Cui, Chem. Commun., 2013, 49, 4968 DOI: 10.1039/C3CC41896K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements