Time-resolved fluorescent detection of Hg2+ in a complex environment by conjugating magnetic nanoparticles with a triple-helix molecular switch

Jing Zheng; Yuhong Nie; Yaping Hu; Jishan Li; Yinhui Li; Ying Jiang; Ronghua Yang

doi:10.1039/C3CC42962H

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Time-resolved fluorescent detection of Hg²⁺ in a complex environment by conjugating magnetic nanoparticles with a triple-helix molecular switch†

Jing Zheng,‡^a Yuhong Nie,‡^a Yaping Hu,^a Jishan Li,^a Yinhui Li,^a Ying Jiang^a and Ronghua Yang*^a

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* Corresponding authors

^a State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, P. R. China
E-mail: Yangrh@pku.edu.cn
Fax: +86-731-88822523
Tel: +86-731-88822523

Abstract

In this communication, we molecularly engineered a light-switching excimer oligonucleotide-based probe for time-resolved fluorescent detection of Hg²⁺. By combining a time-resolved fluorescence technique and magnetic nanoparticles, Hg²⁺ spiked in human urine was detected.

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Article information

DOI: https://doi.org/10.1039/C3CC42962H
Article type: Communication
Submitted: 22 Apr 2013
Accepted: 11 Jun 2013
First published: 11 Jun 2013

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Chem. Commun., 2013,49, 6915-6917

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Time-resolved fluorescent detection of Hg²⁺ in a complex environment by conjugating magnetic nanoparticles with a triple-helix molecular switch

J. Zheng, Y. Nie, Y. Hu, J. Li, Y. Li, Y. Jiang and R. Yang, Chem. Commun., 2013, 49, 6915 DOI: 10.1039/C3CC42962H

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Chemical Communications