Issue 77, 2013
From the journal:

Chemical Communications

One-pot one-step deracemization of amines using ω-transaminases†

Giyoung Shin,a   Sam Mathew,a   Minsu Shon,a   Byung-Gee Kimb  and  Hyungdon Yun*a  

* Corresponding authors

a School of Biotechnology, Yeungnam University, Gyeongsan, Gyeongbuk, South Korea
E-mail: hyungdon@ynu.ac.kr
Fax: +82-53-810-4769
Tel: +82-53-810-3044

b School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, South Korea

Abstract

In this study, we developed a one-pot one-step deracemization method for the production of various enantiomerically pure amines using two opposite enantioselective ω-TAs. Using this method, various aromatic amines were successfully converted to their (R)-forms (>99%) with good conversion.

Graphical abstract: One-pot one-step deracemization of amines using ω-transaminases

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC43348J
Article type
Communication
Submitted
06 May 2013
Accepted
11 Jun 2013
First published
11 Jun 2013

Chem. Commun., 2013,49, 8629-8631

Permissions

Request permissions

One-pot one-step deracemization of amines using ω-transaminases

G. Shin, S. Mathew, M. Shon, B. Kim and H. Yun, Chem. Commun., 2013, 49, 8629 DOI: 10.1039/C3CC43348J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements