Issue 57, 2013
From the journal:

Chemical Communications

Organocatalytic asymmetric remote aziridination of 2,4-dienals†

Kim Søholm Halskov,a   Tricia Naicker,a   Magnus E. Jensena  and  Karl Anker Jørgensen*a  

* Corresponding authors

a Center for Catalysis, Aarhus University,, Langelandsgade 140, DK-8000 Aarhus C, Denmark
E-mail: kaj@chem.au.dk
Tel: +45 8715 5956

Abstract

Highly regio- and stereoselective remote aziridination of 2,4-dienals has been developed, based on a vinylogous iminium-ion–dienamine catalytic cascade reaction. Transformations of the aziridine products into enantioenriched motifs are also demonstrated. Furthermore, the reaction concept is extended to include enantioselective 1,6-addition of thiols.

Graphical abstract: Organocatalytic asymmetric remote aziridination of 2,4-dienals

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC43506G
Article type
Communication
Submitted
10 May 2013
Accepted
29 May 2013
First published
30 May 2013

Chem. Commun., 2013,49, 6382-6384

Permissions

Request permissions

Organocatalytic asymmetric remote aziridination of 2,4-dienals

K. S. Halskov, T. Naicker, M. E. Jensen and K. A. Jørgensen, Chem. Commun., 2013, 49, 6382 DOI: 10.1039/C3CC43506G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements