Issue 73, 2013
From the journal:

Chemical Communications

Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging†

Juan Qiao,a   Xiaoyu Mu,ab   Li Qi,*a   Jingjing Dengab  and  Lanqun Maoa  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems Institute of Chemistry, Chinese Academy of Sciences, No. 2 Zhongguancun Beiyijie, P. R. China
E-mail: qili@iccas.ac.cn
Fax: +86-10-62559373
Tel: +86-10-82627290

b Graduate School, University of Chinese Academy of Sciences, 19A Yuquanlu, Beijing, P. R. China

Abstract

A novel nano-conjugate containing ultrasmall water-soluble AuNCs protected by ovalbumin as the fluorescent part, folic acid as the targeting ligand and a homopolymer N-acryloxysuccinimide as the linker has been investigated. Moreover, specific staining of HeLa cells by the nano-conjugate has been demonstrated.

Graphical abstract: Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging

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Article information

DOI
https://doi.org/10.1039/C3CC44256J
Article type
Communication
Submitted
06 Jun 2013
Accepted
05 Jul 2013
First published
05 Jul 2013

Chem. Commun., 2013,49, 8030-8032

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Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging

J. Qiao, X. Mu, L. Qi, J. Deng and L. Mao, Chem. Commun., 2013, 49, 8030 DOI: 10.1039/C3CC44256J

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