Issue 85, 2013
From the journal:

Chemical Communications

Iron complex-based fluorescent probes for intracellular hydrogen peroxide detection†

Yutaka Hitomi,*a   Toshiyuki Takeyasua  and  Masahito Koderaa  

* Corresponding authors

a Department of Molecular Chemistry and Biochemistry, Doshisha University, 1-3 Tatara Miyakodani, Kyotanabe 610-0321, Japan
E-mail: yhitomi@mail.doshisha.ac.jp

Abstract

A metal-based fluorescent probe for H2O2, named MBFh2, releases a highly fluorescent resorufin in the seconds time scale even in the presence of 5 μM H2O2. The use of MBFh2 enabled the visualization of intracellular H2O2 that was generated after stimulation of the epidermal growth factor.

Graphical abstract: Iron complex-based fluorescent probes for intracellular hydrogen peroxide detection

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Article information

DOI
https://doi.org/10.1039/C3CC44471F
Article type
Communication
Submitted
14 Jun 2013
Accepted
07 Aug 2013
First published
14 Aug 2013

Chem. Commun., 2013,49, 9929-9931

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Iron complex-based fluorescent probes for intracellular hydrogen peroxide detection

Y. Hitomi, T. Takeyasu and M. Kodera, Chem. Commun., 2013, 49, 9929 DOI: 10.1039/C3CC44471F

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