Issue 77, 2013
From the journal:

Chemical Communications

An ICT-based fluorescent switch-on probe for hydrogen sulfide in living cells†

Xin Li,*a   Shuai Zhang,a   Ji Cao,b   Nan Xie,b   Tao Liu,a   Bo Yang,b   Qiaojun Heb  and  Yongzhou Hu*a  

* Corresponding authors

a ZJU-ENS Joint Laboratory of Medicinal Chemistry, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
E-mail: lixin81@zju.edu.cn
Fax: +86-571-88981051
Tel: +86-571-88981051

b Institute of Pharmacology and Toxicology, College of Pharmaceutical Sciences, Zhejiang University, China

Abstract

An ICT-based fluorescent turn-on probe for hydrogen sulfide with high selectivity has been designed and synthesized. It exhibits up to 62-fold switch-on response toward H2S at given concentrations and can detect H2S in living cells with high sensitivity.

Graphical abstract: An ICT-based fluorescent switch-on probe for hydrogen sulfide in living cells

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Article information

DOI
https://doi.org/10.1039/C3CC44539A
Article type
Communication
Submitted
19 Jun 2013
Accepted
31 Jul 2013
First published
31 Jul 2013

Chem. Commun., 2013,49, 8656-8658

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An ICT-based fluorescent switch-on probe for hydrogen sulfide in living cells

X. Li, S. Zhang, J. Cao, N. Xie, T. Liu, B. Yang, Q. He and Y. Hu, Chem. Commun., 2013, 49, 8656 DOI: 10.1039/C3CC44539A

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