Issue 80, 2013

Monosubstituted alkenyl amino acids for peptide “stapling”

Abstract

Alkenylglycine amino acids were assessed as potential candidates for hydrocarbon stapling and shown to be effective in stapling of the BID BH3 peptide.

Graphical abstract: Monosubstituted alkenyl amino acids for peptide “stapling”

Supplementary files

Article information

Article type
Communication
Submitted
11 Jul 2013
Accepted
27 Aug 2013
First published
04 Sep 2013
This article is Open Access

Chem. Commun., 2013,49, 9131-9133

Monosubstituted alkenyl amino acids for peptide “stapling”

D. J. Yeo, S. L. Warriner and A. J. Wilson, Chem. Commun., 2013, 49, 9131 DOI: 10.1039/C3CC45231J

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