Issue 97, 2013
From the journal:

Chemical Communications

Iron oxide-loaded hollow mesoporous silica nanocapsules for controlled drug release and hyperthermia†

Feng Lu,‡ab   Adriana Popa,‡a   Shiwei Zhou,b   Jun-Jie Zhu*b  and  Anna Cristina S. Samia*a  

* Corresponding authors

a Department of Chemistry, Case Western Reserve University, 10900 Euclid Ave., Cleveland, OH, USA
E-mail: anna.samia@case.edu
Fax: +1 (216)368-3006
Tel: +1 (216)368-3852

b State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China
E-mail: jjzhu@nju.edu.cn
Fax: +86-25-8359-7204
Tel: +86-25-8359-7204

Abstract

Magnetic field-responsive iron oxide-loaded hollow mesoporous silica nanocapsules that exhibit high drug loading capacity were synthesized using polymer nanospheres as sacrificial templates. Due to their magnetic field induced heating and remotely triggered drug release capabilities, these hybrid nanomaterials provide an excellent platform for the combination of hyperthermia and chemotherapy.

Graphical abstract: Iron oxide-loaded hollow mesoporous silica nanocapsules for controlled drug release and hyperthermia

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Article information

DOI
https://doi.org/10.1039/C3CC46658B
Article type
Communication
Submitted
30 Aug 2013
Accepted
15 Oct 2013
First published
30 Oct 2013

Chem. Commun., 2013,49, 11436-11438

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Iron oxide-loaded hollow mesoporous silica nanocapsules for controlled drug release and hyperthermia

F. Lu, A. Popa, S. Zhou, J. Zhu and A. C. S. Samia, Chem. Commun., 2013, 49, 11436 DOI: 10.1039/C3CC46658B

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