Issue 97, 2013
From the journal:

Chemical Communications

Photodegradation of β-sheet amyloid fibrils associated with Alzheimer's disease by using polyoxometalates as photocatalysts†

Meng Li,a   Can Xu,a   Jinsong Ren,a   Enbo Wangb  and  Xiaogang Qu*a  

* Corresponding authors

a Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences, Changchun, Jilin 130022, China
E-mail: xqu@ciac.ac.cn

b Key Laboratory of Polyoxometalate Science of the Ministry of Education, Northeast Normal University, Changchun, Jilin 130024, China

Abstract

Herein we report that POMs can not only inhibit Aβ aggregation but also photodegrade Aβ, especially the oligomers, showing enhanced inhibition effects.

Graphical abstract: Photodegradation of β-sheet amyloid fibrils associated with Alzheimer's disease by using polyoxometalates as photocatalysts

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Article information

DOI
https://doi.org/10.1039/C3CC46772D
Article type
Communication
Submitted
05 Sep 2013
Accepted
14 Oct 2013
First published
15 Oct 2013

Chem. Commun., 2013,49, 11394-11396

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Photodegradation of β-sheet amyloid fibrils associated with Alzheimer's disease by using polyoxometalates as photocatalysts

M. Li, C. Xu, J. Ren, E. Wang and X. Qu, Chem. Commun., 2013, 49, 11394 DOI: 10.1039/C3CC46772D

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