Issue 11, 2013
From the journal:

Green Chemistry

Easy conjugations between molecules via copper-catalyzed reactions of ortho-aromatic diamines with ketones†

Juyou Lu,ab   Haijun Yang,a   Yunhe Jin,a   Yuyang Jiangc  and  Hua Fu*ac  

* Corresponding authors

a Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China
E-mail: fuhua@mail.tsinghua.edu.cn
Fax: (+86) 10-62781695

b Xi'an Modern Chemistry Research Institute, Xi'an 710065, P. R. China

c Key Laboratory of Chemical Biology (Guangdong Province), Graduate School of Shenzhen, Tsinghua University, Shenzhen 518057, P. R. China

Abstract

It is a great challenge to achieve a useful reaction under benign conditions. In this paper, a highly efficient method for copper-catalyzed conjugations of o-aromatic diamines with ketones has been developed using benign chemistry. Interestingly, the conjugation between the biological small molecules worked very well.

Graphical abstract: Easy conjugations between molecules via copper-catalyzed reactions of ortho-aromatic diamines with ketones

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Article information

DOI
https://doi.org/10.1039/C3GC41585F
Article type
Communication
Submitted
04 Aug 2013
Accepted
10 Sep 2013
First published
10 Sep 2013

Green Chem., 2013,15, 3184-3187

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Easy conjugations between molecules via copper-catalyzed reactions of ortho-aromatic diamines with ketones

J. Lu, H. Yang, Y. Jin, Y. Jiang and H. Fu, Green Chem., 2013, 15, 3184 DOI: 10.1039/C3GC41585F

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