Issue 18, 2013
From the journal:

Lab on a Chip

Cell pairing using a dielectrophoresis-based device with interdigitated array electrodes

Mustafa Şen,a   Kosuke Ino,*a   Javier Ramón-Azcón,b   Hitoshi Shikua  and  Tomokazu Matsue*ab  

* Corresponding authors

a Graduate School of Environmental Studies, Tohoku University, Sendai 980-8579, Japan
E-mail: ino.kosuke@bioinfo.che.tohoku.ac.jp
Fax: +81-22-795-7281
Tel: +81-22-795-7281

b WPI-Advanced Institute for Materials Research, Tohoku University, Sendai 980-8579, Japan
E-mail: matsue@bioinfo.che.tohoku.ac.jp
Fax: +81-22-795-7209
Tel: +81-22-795-7209

Abstract

We present a chip device with an array of 900 gourd-shaped microwells designed to pair single cells of different types. The device consists of interdigitated array (IDA) electrodes and uses positive dielectrophoresis to trap cells within the microwells. Each side of a microwell is on a different comb of the IDA, so that cells of different types are trapped on opposite sides of the microwells, leading to close cell pairing. Using this device, a large number of cell pairs can be formed easily and rapidly, making it a highly attractive tool for controllable cell pairing in a range of biological applications.

Graphical abstract: Cell pairing using a dielectrophoresis-based device with interdigitated array electrodes

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Article information

DOI
https://doi.org/10.1039/C3LC50561H
Article type
Communication
Submitted
07 May 2013
Accepted
02 Jul 2013
First published
03 Jul 2013

Lab Chip, 2013,13, 3650-3652

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Cell pairing using a dielectrophoresis-based device with interdigitated array electrodes

M. Şen, K. Ino, J. Ramón-Azcón, H. Shiku and T. Matsue, Lab Chip, 2013, 13, 3650 DOI: 10.1039/C3LC50561H

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