Issue 8, 2013
From the journal:

Nanoscale

A single-molecule force spectroscopy study of the interactions between lectins and carbohydrates on cancer and normal cells†

Weidong Zhao,ab   Mingjun Cai,a   Haijiao Xu,a   Junguang Jianga  and  Hongda Wang*ab  

* Corresponding authors

a State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P. R. China
E-mail: hdwang@ciac.jl.cn
Fax: +86 0431 2804
Tel: +86 0431 2453

b University of Chinese Academy of Sciences, Beijing 100049, P. R. China

Abstract

The interaction forces between carbohydrates and lectins were investigated by single-molecule force spectroscopy on both cancer and normal cells. The binding kinetics was also studied, which shows that the carbohydrate–lectin complex on cancer cells is less stable than that on normal cells.

Graphical abstract: A single-molecule force spectroscopy study of the interactions between lectins and carbohydrates on cancer and normal cells

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3NR00553D
Article type
Communication
Submitted
31 Jan 2013
Accepted
25 Feb 2013
First published
26 Feb 2013

Nanoscale, 2013,5, 3226-3229

Permissions

Request permissions

A single-molecule force spectroscopy study of the interactions between lectins and carbohydrates on cancer and normal cells

W. Zhao, M. Cai, H. Xu, J. Jiang and H. Wang, Nanoscale, 2013, 5, 3226 DOI: 10.1039/C3NR00553D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements