Highly enantioselective hydrosilylation of N-(1,2-diarylethylidene)arylamines

Abstract

By employing a chiral Lewis base as the catalyst, enantioselective hydrosilylation of N-(1,2-diarylethylidene)arylamines was realized. The reactions proceeded smoothly to afford various chiral 1,2-diarylethanamines with good yields (up to 99%) in good enantioselectivities (up to 98%). Furthermore, one of the products was employed in the synthesis of a pharmaceutical substance.