Issue 1, 2013

N-heterocyclic carbene-catalyzed [4 + 2] cycloaddition of ketenes and 3-aroylcoumarins: highly enantioselective synthesis of dihydrocoumarin-fused dihydropyranones

Abstract

The N-heterocyclic carbene-catalyzed [4 + 2] cyclization of ketenes and 3-aroylcoumarins has been developed to give the corresponding dihydrocoumarin-fused multisubstituted dihydropyranones in high yield with good diastereoselectivity and high enantioselectivity.

Graphical abstract: N-heterocyclic carbene-catalyzed [4 + 2] cycloaddition of ketenes and 3-aroylcoumarins: highly enantioselective synthesis of dihydrocoumarin-fused dihydropyranones

Supplementary files

Article information

Article type
Paper
Submitted
14 Sep 2012
Accepted
12 Oct 2012
First published
16 Oct 2012

Org. Biomol. Chem., 2013,11, 158-163

N-heterocyclic carbene-catalyzed [4 + 2] cycloaddition of ketenes and 3-aroylcoumarins: highly enantioselective synthesis of dihydrocoumarin-fused dihydropyranones

T. Jian, X. Chen, L. Sun and S. Ye, Org. Biomol. Chem., 2013, 11, 158 DOI: 10.1039/C2OB26804C

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