CAL-B catalyzed desymmetrization of 3-alkylglutarate: “olefin effect” and asymmetric synthesis of pregabalin†
Abstract
CAL-B catalyzed desymmetrization of prochiral 3-alkylglutaric acid
* Corresponding authors
a
Department of Chemistry and Protein Research Center for Bio-Industry, Hankuk University of Foreign Studies, Yongin, Kyunggi-Do 449-719, Korea
E-mail:
hjha@hufs.ac.kr
Tel: +82-31-330-4369
b
Department of Chemistry, Sogang University, Seoul 121-742, Korea
E-mail:
wonkoo@sogang.ac.kr
Tel: +82-2-705-8449
CAL-B catalyzed desymmetrization of prochiral 3-alkylglutaric acid
J. Jung, D. Yoon, P. Kang, W. K. Lee, H. Eum and H. Ha, Org. Biomol. Chem., 2013, 11, 3635 DOI: 10.1039/C3OB40311D
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