Cyclization–carbonylation–cyclizationcoupling reaction of α,β-alkynic hydrazones with palladium(ii)-bisoxazoline catalyst

Abstract

A cyclization–carbonylation–cyclization coupling reaction (CCC-coupling reaction) of α,β-alkynic hydrazones, catalyzed by (box)Pd^II complexes, afforded symmetrical ketones bearing two pyrazole groups in good to excellent yields. This method is applicable to a broad range of substrates.