Issue 11, 2013

Biodegradable polymer network encapsulated polyplex for DNA delivery

Abstract

A novel gene delivery system is made by encapsulation of a polyplex between pDNA and cationic micelles with a biodegradable crosslinked shell. The outer shell can provide additional functionality to the system and protect DNA from degradation. The encapsulated polyplex exhibits a similar transfection efficiency compared to the naked polyplex.

Graphical abstract: Biodegradable polymer network encapsulated polyplex for DNA delivery

Supplementary files

Article information

Article type
Communication
Submitted
22 Aug 2012
Accepted
11 Jan 2013
First published
14 Jan 2013

RSC Adv., 2013,3, 3508-3511

Biodegradable polymer network encapsulated polyplex for DNA delivery

P. D. Petrov, N. I. Ivanova, M. D. Apostolova and C. B. Tsvetanov, RSC Adv., 2013, 3, 3508 DOI: 10.1039/C3RA21890B

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