Direct C-arylation of polyfluoroarenes with diaryliodonium salts via Pd(OAc)2-catalysis

Abstract

A novel approach towards the Pd-catalyzed arylation of electron-deficient polyfluoroarenes with diaryliodonium salts was developed. The desired fluorinated biaryls were synthesized in good yields. The mechanistic insights involving the Pd^II/IV catalytic cycle for the present reaction were discussed, which will be helpful in the understanding of catalytic arylations with diaryliodonium salts.