Issue 27, 2013
From the journal:

RSC Advances

Silver nanoshells as tri-mode bactericidal agents integrating long term antibacterial, photohyperthermia and triggered Ag+ release capabilities

Da Huo,ab   Jian Gao,ab   Binglei Guo,b   Yin Ding,c   Jian He,a   HaiPing Yu,a   Zhengyang Zhou*a  and  Yong Hu*b  

* Corresponding authors

a Department of Radiology, Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, P. R. China
E-mail: zzy@nju.edu.cn
Fax: +86 025 83594668
Tel: +86 025 83594668

b Institute of Materials Engineering, National Laboratory of Solid State Microstructure College of Engineering and Applied Sciences, Nanjing University, Nanjing, Jiangsu, P. R. China

c State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu, P. R. China
E-mail: hvyong@nju.edu.cn

Abstract

Novel polymer–silver hybrid core–shell nanoparticles (SNSs) which showed long term bacteriostatic, photohyperthermia induced bactericidal and triggered Ag+ release abilities were reported. Both gram-negative (GN) and gram-positive (GP) bacteria can be effectively killed by photothermolysis therapy. The Ag+ release triggered by illumination provides a sustained release of Ag+, which offers long term antibacterial ability under normal conditions.

Graphical abstract: Silver nanoshells as tri-mode bactericidal agents integrating long term antibacterial, photohyperthermia and triggered Ag+ release capabilities

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Article information

DOI
https://doi.org/10.1039/C3RA40417J
Article type
Communication
Submitted
25 Jan 2013
Accepted
09 May 2013
First published
09 May 2013

RSC Adv., 2013,3, 10632-10638

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Silver nanoshells as tri-mode bactericidal agents integrating long term antibacterial, photohyperthermia and triggered Ag+ release capabilities

D. Huo, J. Gao, B. Guo, Y. Ding, J. He, H. Yu, Z. Zhou and Y. Hu, RSC Adv., 2013, 3, 10632 DOI: 10.1039/C3RA40417J

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