Issue 4, 2013

Sequential and phototriggered supramolecular self-sorting cascades using hydrogen-bonded motifs

Abstract

A series of hydrogen-bonding motifs are shown to be capable of both high-fidelity and promiscuous molecular recognition behaviour. This gives rise to self-sorting and therefore well defined product distributions for up to four sequential phases of building block composition. Inclusion of a hydrogen-bonding motif that becomes capable of molecular recognition only upon photo-cleavage, extends the number of phases in the cascade to five. This supramolecular system thus reproduces multiple features of biological signalling cascades including the ability to switch between successive states comprising multiple well-defined complexes and triggered modification of molecular recognition preferences.

Graphical abstract: Sequential and phototriggered supramolecular self-sorting cascades using hydrogen-bonded motifs

Supplementary files

Article information

Article type
Edge Article
Submitted
10 Dec 2012
Accepted
08 Feb 2013
First published
11 Feb 2013
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry

Chem. Sci., 2013,4, 1825-1829

Sequential and phototriggered supramolecular self-sorting cascades using hydrogen-bonded motifs

M. L. Pellizzaro, K. A. Houton and A. J. Wilson, Chem. Sci., 2013, 4, 1825 DOI: 10.1039/C3SC22194F

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