Issue 21, 2014
From the journal:

Analyst

Green electrochemical sensing platforms: utilizing hydroxyapatite derived from natural fish scales as a novel electrochemical material for the sensitive detection of kidney injury molecule 1 (KIM-1)†

Ying Zhang,a   Wei Zhang,b   Qing Zhang,c   Kaiyang Li,c   Wei Liu,*a   Yong Liu*c  and  Craig E. Banks*d  

* Corresponding authors

a National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, P.R. China
E-mail: wliu@hust.edu.cn
Fax: +86-027-87792234
Tel: +86-027-87792234

b 712th Research Institute, China Shipbuilding Industry Corporation, Wuhan, P.R. China

c State Key Laboratory of Powder Metallurgy, Central South University, Changsha, P.R. China
E-mail: yonliu@csu.edu.cn
Fax: +86-731-88836939
Tel: +86-731-88836939

d Faculty of Science and Engineering, School of Science and the Environment, Division of Chemistry and Environmental Science, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, Lancs, UK
E-mail: c.banks@mmu.ac.uk
Web: http://www.craigbanksresearch.com
Fax: +44 (0)1612476831
Tel: +44 (0)1612471196

Abstract

Urinary KIM-1 is an ideal biomarker for acute kidney injury diagnosis. The proof-of-concept is demonstrated by utilizing the hydroxyapatite derived from natural fish scales as an electrode material, where the sensing of KIM-1 is shown to be possible for the first time with a linear range from 0.01 to 0.20 μg mL−1 and a detection limit of 0.017 μg mL−1 under model conditions; proof-of-concept is demonstrated in spiked urine.

Graphical abstract: Green electrochemical sensing platforms: utilizing hydroxyapatite derived from natural fish scales as a novel electrochemical material for the sensitive detection of kidney injury molecule 1 (KIM-1)

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Article information

DOI
https://doi.org/10.1039/C4AN00957F
Article type
Communication
Submitted
27 May 2014
Accepted
14 Aug 2014
First published
05 Sep 2014
This article is Open Access
Creative Commons BY-NC license

Analyst, 2014,139, 5362-5366

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Green electrochemical sensing platforms: utilizing hydroxyapatite derived from natural fish scales as a novel electrochemical material for the sensitive detection of kidney injury molecule 1 (KIM-1)

Y. Zhang, W. Zhang, Q. Zhang, K. Li, W. Liu, Y. Liu and C. E. Banks, Analyst, 2014, 139, 5362 DOI: 10.1039/C4AN00957F

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