Complex biological matrices can be effectively removed in the analyte migration process because of their weak solubility in organic solvents. This technique offers other potential advantages, including high-sensitivity and the capability of performing a direct analysis of the components and their metabolites in small-volume raw samples without any pretreatment.
Q. Wang, H. Zhong, Y. Zheng, S. Zhang, X. Liu, X. Zhang, X. Zhang and Z. Zhang, Analyst, 2014, 139, 5678 DOI: 10.1039/C4AN01397B
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