Colorimetric detection of ATP with DNAzyme: design an activatable hairpin probe for reducing background signals and improving selectivity

Abstract

On the basis of the phenomenon that ATP can induce the formation and increase the catalytic activity of the G-quadruplex, an activatable hairpin DNA probe, which includes the HRP-mimicking G-quadruplex, was designed and utilized for low-background and high-selective colorimetric detection of ATP.