Catalytic oxidation of alkanes by iron bispidine complexes and dioxygen: oxygen activation versus autoxidation

Abstract

Organic substrates (specifically cis-1,2-dimethylcyclohexane, DMCH) are oxidized by O₂ in the presence of iron(II)–bispidine complexes. It is shown that this oxidation reaction is not based on O₂ activation by the nonheme iron catalysts as in Nature but due to a radical-based initiation, followed by a radical- and ferryl-based catalytic reaction.