Issue 1, 2014
From the journal:

Chemical Communications

An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity†

Young Seop Kwon,‡a   Nurul Hanun Ahmad Raston‡a  and  Man Bock Gu*a  

* Corresponding authors

a School of Life Sciences and Biotechnology, Korea University, Anam-dong, Seongbuk-Gu, Seoul 136-713, Republic of Korea
E-mail: mbgu@korea.ac.kr
Fax: +82-2-9286050
Tel: +82-2-3290-3417

Abstract

A shortened 8-mer ssDNA aptamer was successfully truncated for four different tetracyclines with high affinity. The ultrasensitive colorimetric detection of oxytetracycline using this shortened aptamer was possible, which was about 500-fold enhanced compared to that obtained using the original 76-mer aptamer.

Graphical abstract: An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

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Article information

DOI
https://doi.org/10.1039/C3CC47108J
Article type
Communication
Submitted
17 Sep 2013
Accepted
12 Oct 2013
First published
17 Oct 2013

Chem. Commun., 2014,50, 40-42

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An ultra-sensitive colorimetric detection of tetracyclines using the shortest aptamer with highly enhanced affinity

Y. S. Kwon, N. H. Ahmad Raston and M. B. Gu, Chem. Commun., 2014, 50, 40 DOI: 10.1039/C3CC47108J

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