Issue 7, 2014
From the journal:

Chemical Communications

Stabilizing vitamin D3 by conformationally selective co-crystallization†

Jian-Rong Wang,a   Chun Zhou,a   Xueping Yua  and  Xuefeng Mei*a  

* Corresponding authors

a Pharmaceutical Analytical & Solid-State Chemistry Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
E-mail: xuefengmei@simm.ac.cn
Fax: +862150807088
Tel: +862150800934

Abstract

A four-membered square-shaped H-bonding structure was successfully designed to synthesize vitamin D3 co-crystals. The co-crystallization process was found to be conformationally selective to result in topochemically stable materials.

Graphical abstract: Stabilizing vitamin D3 by conformationally selective co-crystallization

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Article information

DOI
https://doi.org/10.1039/C3CC47747A
Article type
Communication
Submitted
09 Oct 2013
Accepted
11 Nov 2013
First published
12 Nov 2013

Chem. Commun., 2014,50, 855-858

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Stabilizing vitamin D3 by conformationally selective co-crystallization

J. Wang, C. Zhou, X. Yu and X. Mei, Chem. Commun., 2014, 50, 855 DOI: 10.1039/C3CC47747A

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