Issue 21, 2014
From the journal:

Chemical Communications

Recognition and neutralization of angiotensins I and II using an artificial nanogel receptor fabricated by ligand specificity determinant imprinting†

Zerong Yu,a   Zhiguang Xu,a   He Li,*a   Jianwen Chen,b   Zhiying Huangb  and  Youwen Tang*a  

* Corresponding authors

a School of Chemistry and Environment, MOE Key Laboratory of Laser Life Science, South China Normal University, 510006 Guangzhou, China
E-mail: tanglab@scnu.edu.cn
Fax: +86-20-39310187
Tel: +86-20-39310369

b School of Pharmaceutical Sciences, Sun Yat-Sen University, 510006 Guangzhou, China

Abstract

A nanogel combined with a molecularly imprinted polymer (MIP-nanogel) receptor was prepared using the specificity determinant as a template in aqueous media. The artificial receptor can serve as the selective recognition element for angiotensins I and II and a novel way to control hypertension was investigated.

Graphical abstract: Recognition and neutralization of angiotensins I and II using an artificial nanogel receptor fabricated by ligand specificity determinant imprinting

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Article information

DOI
https://doi.org/10.1039/C3CC48152B
Article type
Communication
Submitted
24 Oct 2013
Accepted
09 Jan 2014
First published
17 Jan 2014

Chem. Commun., 2014,50, 2728-2731

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Recognition and neutralization of angiotensins I and II using an artificial nanogel receptor fabricated by ligand specificity determinant imprinting

Z. Yu, Z. Xu, H. Li, J. Chen, Z. Huang and Y. Tang, Chem. Commun., 2014, 50, 2728 DOI: 10.1039/C3CC48152B

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