nBu4NI-Catalyzed oxidative imidation of ketones with imides: synthesis of α-amino ketones

Abstract

nBu₄NI-Catalyzed oxidative imidation of ketones and imides for the synthesis of α-amino ketones were realized for the first time. The methodology is characterized by its wide substrate scope even for acetone with readily available phthalimide, saccharin and succinimide, which opens a new pathway for direct imidation of ketones.